Dermatology Pediatrics in Israel: June 2011

Saturday, June 18, 2011

Verrucous Carcinoma of the Lip: An Unusual Kissing Type

1Article first published online: 7 JUN 2011

DOI: 10.1111/j.1524-4725.2011.02066.x

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Immunohistological Evaluation of Skin Responses After Treatment Using a Fractional Ultrapulse Carbon Dioxide Laser on Back Skin

XUE‐GANG XU MD1,2,†, YAO‐JIA LUO MD1,†, YAN WU MD, PHD1, JOHN ZS CHEN MD, PHD3, TIAN‐HUA XU MD, PHD1, XING‐HUA GAO MD, PHD1, CHUN‐DI HE MD, PHD1, LONG GENG MD, PHD1, TING XIAO MD, PHD1, YA‐QIN ZHANG MD, PHD2, HONG‐DUO CHEN MD1, YUAN‐HONG LI MD, PHD1Article first published online: 7 JUN 2011

DOI: 10.1111/j.1524-4725.2011.02062.x

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Treatments for common and plantar warts

Jan Nico Bouwes Bavinck, dermatologist1, Just A H Eekhof, general practitioner2, Sjoerd C Bruggink, general practitioner2 1Department of Dermatology, Leiden University Medical Centre, Leiden, 2333 ZA Leiden, Netherlands 2Department of Public Health and Primary Care, Leiden University Medical Centre j.n.bouwes_bavinck

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Cryotherapy versus salicylic acid for the treatment of plantar warts (verrucae): a randomised controlled trial

OPEN ACCESS Sarah Cockayne, research fellow1, Catherine Hewitt, statistician1, Kate Hicks, research fellow1, Shalmini Jayakody, trial statistician1, Arthur Ricky Kang’ombe, trial statistician1, Eugena Stamuli, trial health economist1, Gwen Turner, trials support officer1, Kim Thomas, associate professor2, Mike Curran, senior lecturer podiatry3, Gary Denby, research assistant3, Farina Hashmi, senior lecturer4, Caroline McIntosh, senior lecturer5, Nichola McLarnon, senior lecturer6, David Torgerson, professor, director of York Trials Unit1, Ian Watt, professor, primary care17 on behalf of the EVerT Team 1Department of Health Sciences, York Trials Unit, University of York, York YO10 5DD, UK 2Centre of Evidence Based Dermatology, University of Nottingham, UK 3School of Health, University of Northampton, UK 4University of Brighton, School of Health Professions, UK 5The National University of Ireland, Galway, Discipline of Podiatry, Galway, Ireland 6Glasgow Caledonian University, School of Health and Social Care, UK 7Hull York Medical School, UK Corresponding to: S Cockayne sarah.cockayne

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Refer scalp lumps requiring excisional biopsy to a surgeon

bedfordhospital.nhs.uk Batchelor and Handfield-Jones’s recommendation that cases of diagnostic uncertainty should be urgently referred to a dermatologist in secondary care does not stand up. 1 Of the three cases presented, two needed

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The frequency of dual TCR‐PCR clonality in granulomatous disorders

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Alteration of stratum corneum ceramide profiles in spontaneous canine model of atopic dermatitis

Ji‐Seon Yoon1, Koji Nishifuji1, Ako Sasaki1, Kaori Ide1, Junko Ishikawa2, Toru Yoshihara2, Toshiroh Iwasaki1Article first published online: 7 JUN 2011

DOI: 10.1111/j.1600-0625.2011.01306.x

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Generalized Pustular Psoriasis Successfully Treated With Granulocyte and Monocyte Adsorption Apheresis

Article first published online: 7 JUN 2011

DOI: 10.1111/j.1744-9987.2011.00961.x

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Letter to the Editor.

Noli C, Morris D.Source

Servizi Dermatologici Veterinari, Via Vocaturo 13, 12016 Peveragno (CN), Italy University of Pennsylvania School of Veterinary Medicine, 3900 Delancey St., Philadelphia, PA 19104, USA.

PMID: 21645142

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Bacterial contamination of commercial ear cleaners following routine home use.

Bartlett SJ, Rosenkrantz WS, Sanchez S.Source

Animal Dermatology Clinic, Marietta, GA 30062, USA Animal Dermatology Clinic, Tustin, CA 92780, USA Department of Infectious Diseases and Athens Veterinary Diagnostic Laboratory, University of Georgia, Athens, GA 30602, USA.

Abstract

Ear cleaning solutions are designed for repeated use, which raises the possibility for bacterial contamination leading to recurrent or persistent infectious otitis. The purpose of this study was to investigate the prevalence of bacterial contamination of commercial ear cleaners following routine home use in dogs and to describe the characteristics that are associated with contamination. Used ear cleaner bottles and information regarding their use were obtained from canine owners visiting veterinary dermatologists. Both the bottle applicator tips and the solution contents were cultured for aerobic bacteria. Bacterial contamination was present on 10% of the bottle tips and in 2% of the solutions. Isolated bacteria included Staphylococcus pseudintermedius, Bacillus spp., coagulase-negative Staphylococcus spp., Micrococcus spp. and Burkholderia cepacia. The contamination rate was significantly higher on the applicator tips than in the solutions (P

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World's First Clinical Trial Of Pioneering Stem Cell Bandage To Treat Torn Meniscal Cartilage

RetweetMain Category: Dermatology
Also Included In: Arthritis / Rheumatology; Clinical Trials / Drug Trials; Stem Cell Research
Article Date: 05 Jun 2011 - 5:00 PDT

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Moberg Derma AB: Moberg Derma Obtains Approval For Treatment For Atopic Eczema And Dry Skin

Moberg Derma AB (publ.) (STO:MOB) today announced that CE mark has been granted for Kaprolac Skin Repair & Hydration, a product designed to treat atopic eczema and dry skin. This CE mark provides authorization to market and sell the product in the EU/EEA.

Kaprolac Skin Repair & Hydration is a new, steroid-free treatment option for eczema and dry skin, such as atopic eczema. Treatment of eczema is a field which has been dominated by older products, with few new launches over the past few years, and Kaprolac Skin Repair & Hydration has properties which meet significant needs in the treatment of atopic eczema.

"We are now looking forward to working together with partners and distributors to make this product available to patients. The benign safety profile makes this Kaprolac product an interesting alternative for patients who are affected by recurrent and protracted problems with eczema. In a comparative study, the product demonstrated a greater ability to reinforce the skin barrier and re-hydrate the skin than a topical pharmaceutical based on propylene glycol," comments Peter Wolpert, CEO of Moberg Derma.

About the product and atopic eczema

Kaprolac Skin Repair & Hydration is a steroid-free treatment for eczema, for topical use, which is designed to treat the most common discomforts such as thickened, dry, itchy and red skin. In clinical trials, treatment with Kaprolac Skin Repair & Hydration led to a statistically significant clinical improvement in atopic eczema, and also of the moisture and barrier abilities of the skin. No adverse events were noted.

It is estimated that atopic eczema affects 15-20% of all children and 2-3% of the adult population.

Moberg Derma discloses the information provided herein pursuant to the Securities Markets Act and/or the Financial Instruments Trading Act. The information was submitted for publication on 10 June, 08:00 am.

Source:
Moberg Derma

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New Guidelines Suggest Higher Doses of Vitamin D

Latest Nutrition, Food & Recipes NewsWorries About High Levels of Folic AcidHealth Tip: Buy Healthy Foods on a BudgetFDA Raises Concerns Over Arsenic in ChickensEating Dirt Has Long, Maybe Healthy, HistoryGuidelines Suggest Higher Doses of Vitamin DWant More News? Sign Up for MedicineNet Newsletters!

Endocrine Society Says Vitamin D Deficiency May Be Common in U.S.

By Daniel J. DeNoon
WebMD Health News

Reviewed by Laura J. Martin, MD

June 6, 2011 -- Noting that vitamin D deficiency is "very common in all age groups," new treatment guidelines call for many Americans to take more vitamin D than is currently recommended.

The guidelines, from the Endocrine Society, offer some contradictory advice. They say that virtually everyone in the U.S. should be taking vitamin D supplements, but that only those at risk for vitamin D deficiency should have their vitamin D blood levels checked.

Only those whose serum 25(OH)D blood levels are above 30 ng/mL are getting enough vitamin D. Lower levels are "insufficient," and those with levels below 20 ng/mL are frankly deficient.

But much higher levels are better, says guideline committee chairman Michael F. Holick, MD, PhD, director of the vitamin D skin and bone research lab at Boston University.

"The committee decided that 30 ng/mL is the minimum level, and recommended 40 to 60 ng/mL for both children and adults," Holick said at an online news conference.

So who's at risk of vitamin D deficiency? Quite a few of us:

Children of all agesPregnant and nursing womenObese peopleDarker-skinned Americans, particularly those of African or Hispanic descentAnyone with a malabsorption syndrome, such as cystic fibrosis, Crohn's disease, or inflammatory bowel diseaseAnyone who has had bariatric surgeryAnyone with osteoporosis, osteomalacia, or an elderly person who's had a fall or fracturePeople with chronic kidney diseasePeople with liver failurePeople taking antiseizure medications, glucocorticoids, AIDS drugs, or antifungal drugsPeople with granuloma-forming disorders such as tuberculosis and sarcoidosis

And even more of us are at risk of vitamin D insufficiency, as studies find that it's relatively common for people to have vitamin D levels below 30 ng/mL.

Few foods carry much vitamin D other than salmon and mackerel. Milk and some orange juice is fortified with small doses.

"So if you drank five or six glasses of fortified orange juice and ate salmon every day, you would get all you need," Holick said.

The body makes its own vitamin D if the skin is exposed to direct sunlight. But too much time in the direct sun raises the risk of skin cancer -- and using sunscreen cuts skin vitamin D production by 95%.

Why Take Vitamin D?

Nearly every cell in the body interacts with vitamin D. The activity of many genes -- up to a third of the entire human genome -- is affected by vitamin D.

There's evidence that vitamin D deficiency may increase the risk of many diseases:

Cancer, including colon, prostate, breast, and pancreatic cancerAutoimmune diseases, including type 1 and type 2 diabetes, rheumatoid arthritis, Crohn's disease, and multiple sclerosisInfectious diseases such as fluHeart disease

However, there's no hard evidence that taking vitamin D supplements prevents or treats any of these illnesses.

What the evidence does show is that vitamin D helps the body use calcium to prevent bone loss and to build stronger bones, and that vitamin D prevents falls in the elderly by improving muscle function.

A new study, reported at the annual meeting of the Endocrine Society by Weill-Cornell researcher Richard Bockman, MD, PhD, shows that people are seven times more likely to benefit from the bone drugs Actonel, Boniva, Fosamax, and Zometa if their vitamin D levels are at or above 33 ng/mL.

Why is there so little data on vitamin D and non-bone diseases? Only recently have researchers realized that vitamin D is not harmful at the new, higher doses. Few studies used enough vitamin D to raise blood levels of 25(OH)D above 30 ng/mL.

On the positive side, there is very little evidence that increasing vitamin D levels to 30 to 100 ng/mL is any harm to children or to adults -- except in some people with granuloma-forming disorders or lymphoma.

Recommended Vitamin D Doses

Last November, the Institute of Medicine (IOM) released guidelines suggesting that most Americans and Canadians get enough vitamin D, and recommending modest doses of vitamin D supplements. The new treatment guidelines point to new data suggesting that the IOM recommendations "may be inadequate."

The new guidelines recommend different doses of vitamin D for those at risk of vitamin D deficiency:

Age 0 to 1 year: 400 to 1,000 International Units (IU) dailyAge 1 to 18 years: 600 to 1,000 IU dailyAll adults over age 18: 1,500 to 2,000 IU dailyPregnant or nursing women under age 18: 600 to 1,000 IU dailyPregnant or nursing women over age 18: 1,500 to 2,000 IU daily

Because fat stores vitamin D, obese people may need to take two or three times the usual dose of vitamin D.

The guidelines recommend much larger doses of vitamin D, for a very limited time, for people trying to get their vitamin D levels back up to 30 ng/mL. Such doses should be taken under a doctor's supervision.

The new guidelines, announced at the annual meeting of the Endocrine Society in Boston, will appear in the July issue of the Journal of Clinical Endocrinology and Metabolism.

SOURCES: News conference webcast, Endocrine Society 2011 annual meeting, held June 4-7 in Boston.News release, Hospital for Special Surgery, New YorkHolick, M.F. Journal of Clinical Endocrinology and Metabolism, July 2011, received ahead of print. ©2011 WebMD, LLC. All Rights Reserved.

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Diseases of the male nipple and areola

Walter KrauseArticle first published online: 9 JUN 2011

DOI: 10.1111/j.1610-0387.2011.07720.x

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Cutaneous and Systemic Hypersensitivity Reactions to Metallic Implants

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Photodynamic Therapy in Dermatology

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No need to hold back on milk, nuts in babies

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Parkinson's Disease May Raise Risk of Melanoma

Study Suggests Link Between Parkinson's and Development of Melanoma

By Denise Mann
WebMD Health News

Reviewed by Laura J. Martin, MD

Latest Neurology NewsValidity of Baseline Concussion Tests QuestionedMigraine Plus PTSD 4 Times More Likely in MenModerate Exercise May Cut Risk of 'Silent' StrokeNew Clues on Genetic Causes of AutismChronic Pot Smoking Affects Brain ChemistryWant More News? Sign Up for MedicineNet Newsletters!

June 6, 2011 -- People with Parkinson's disease are at increased risk for developing melanoma, a potentially fatal form of skin cancer, a study shows.

The new findings appear in Neurology.

Close to 1 million people in the U.S. have Parkinson's disease, a progressive neurological disease marked by tremors and difficulty with movement and walking.

The researchers analyzed 12 studies of people with both Parkinson's disease and melanoma. These studies were conducted from 1965 and 2010, and most had fewer than 10 people with both conditions.

When compared to those without Parkinson's disease, men with Parkinson's were twice as likely to develop melanoma. Women with Parkinson's disease were 1.5 times as likely to be diagnosed with this form of skin cancer. Parkinson's disease was not associated with an increased risk of other types of skin cancer.

Exactly how the two conditions are linked is not fully understood. Initially, there was some suspicion that a Parkinson's medication called levodopa may be responsible for this increased risk, but this has not been substantiated. There may be some genetic of environmental risk factor that serves as the common denominator between the two conditions.

"Further research is needed to examine the nature and mechanisms of this relationship in order to advance our understanding about the

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Dermatologic Manifestations as Indicators of Immune Status in HIV/AIDS

email citeulike Connotea Delicious citeulike Medicine Journal of General Internal MedicineDOI: 10.1007/s11606-011-1743-4Online First

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No Need to Hold Back on Milk, Nuts in Babies

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A miRNA-492 binding-site polymorphism in BSG (basigin) confers risk to psoriasis in Central South Chinese population

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Share this item email citeulike Connotea Delicious citeulike Biomedical and Life Sciences Human GeneticsDOI: 10.1007/s00439-011-1026-5Online First

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Optical coherence tomography in dermatology: technical and clinical aspects

email citeulike Connotea Delicious citeulike Medicine Archives of Dermatological ResearchDOI: 10.1007/s00403-011-1152-xOnline First

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Scientists Show For The First Time Why Aqueous Cream Can Only Make Eczema Worse, UK

Article Opinions: 1 posts
Aqueous Cream B.P. which is commonly prescribed for eczema makes the condition worse at the cellular and molecular level.

Eczema currently accounts for 22.5% of skin complaints treated by GPs and the number is rising. Aqueous Cream B.P. is routinely prescribed to eczema sufferers despite evidence linking it to the thinning of the outer layer of the skin. New research conducted at The School of Pharmacy, University of London and published in the British Journal of Dermatology this month demonstrates for the first time why applying Aqueous Cream makes the condition worse as it actually increases the peeling and inflammation of the skin.

The study showed a clear difference between treated and untreated skin. Treated areas became more inflamed and prone to peeling due to an increase in the activity of proteases; enzymes which break down skin protein. There was also a decrease in the size and maturity of skin cells - an essential part of the skin's protective structure. The treated skin also lost significantly more moisture.

Research author, Diar Mohammed said:

"Imagine the skin's protective layer as a 'bricks and mortar' wall-like structure. In those areas that are treated with Aqueous Cream the bricks are smaller and less well-formed. At the same time the 'wall' is being attacked by enzymes which are eating away at the structure. The end result is, of course, a weaker wall. So, rather than soothing the condition, this cream produces exactly the opposite effect making the condition worse at the cellular and molecular level; it effectively causes the skin's 'wall' to collapse causing far more irritation and soreness.

"Aqueous cream is the UK's cheapest and most frequently prescribed emollient. But these results make it clear that being cheap is not enough to justify its continued use."

His PhD supervisor, Dr Majella Lane added:

"This new evidence finally shows exactly why using Aqueous Cream to treat skin complaints is a mistake. We would seriously suggest that consumers seek out alternative treatments.

"The research has considerable implications for the formulation and labelling of such dermatological products. The action of the detergent sodium lauryl sulphate in Aqueous Cream is a cause of many of the issues we have identified. Unfortunately the presence of this key ingredient is often not clearly indicated and we would wish to see far more explicit labelling."

Professor Jonathan Hadgraft, Emeritus Professor of Biophysical Chemistry concluded:

"Despite an increasing consensus that Aqueous Cream damages the skin's structure it continues to be prescribed. We now have clear evidence of precisely how this emollient can only make skin complaints worse."

Source:
The School of Pharmacy, University of London
Skin Research Centre

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Life‐style factors and hand eczema

Anveden Berglind I, Alderling M, Meding B.Source

Unit of Occupational and Environmental Dermatology - Institute of Environmental Medicin, Karolinska Institutet, Norrbacka plan 3, Stockholm 17176, Sweden.

Abstract

Background: Previous knowledge of the impact of certain life-style factors on hand eczema is scanty. Objectives: To investigate a possible association between hand eczema and life-style factors such as obesity, physical exercise, stress, smoking and alcohol consumption. Method: In a cross-sectional public health survey in Stockholm, Sweden, 27 994 (58%) randomly chosen individuals aged 18-64 years completed a postal questionnaire regarding physical and mental health, social relations, economic status and work. Of these 27 793 individuals responded to the question regarding hand eczema and were included in the present study. The association between life-style factors and hand eczema was analysed by prevalence proportion ratios (PPR), using a generalised linear model. Results: Hand eczema was more common among individuals who reported high stress levels, PPR 1.326 (95%CI 1.303-1.350). There was also a positive dose-response relation between hand eczema and stress. Hand eczema was less common among individuals reporting high physical exercise, most apparent in women, PPR 0.781 (95%CI 0.770-0.792). Men who reported high alcohol intake less often reported hand eczema, PPR 0.958 (95%CI 0.930-0.987). Obese individuals reported hand eczema more commonly, PPR 1.204 (95%CI 1.174-1.234). There was a slight increase of hand eczema among smokers, PPR 1.025 (95%CI 1.006-1.044). Conclusions: Hand eczema was more common in individuals who reported stress, obesity and smoking. In individuals who reported high physical exercise levels hand eczema was less common. As there appears to be an association between life-style factors and hand eczema it is important to consider life-style factors in clinical practice.

Friday, June 17, 2011

ECZEMA HEADACHE (Giant Puffball ) Pellet [Natural Health Supply]

Daily Med Current Medication Information Options Home E-mail Label InformationDownloadsDownload All Drug LabelsDownload this Label(XML)FDA SPL XML SchemaSPL History Print this Label Download this Label (PDF) Notify of Updates Contact UsAdditional ResourcesReport Adverse Event MedlinePlus Information Find Clinical TrialsBiochemical Data Summary Search PubMed Articles All CitationsAdverse EffectsTherapeutic UsePharmacologyClinical Trials Presence in Breast Milk

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Pediatric allergy and immunology in Italy

Alberto E. Tozzi1, Lucio Armenio2, Roberto Bernardini3, Attilio Boner4, Mauro Calvani5, Fabio Cardinale6, Giovanni Cavagni7, Arianna Dondi8, Marzia Duse9, Alessandro Fiocchi10, Gian L. Marseglia11, Michele Miraglia del Giudice12, Antonella Muraro13, Giovanni B. Pajno14, Francesco Paravati15, Diego Peroni4, Salvatore Tripodi16, Alberto G. Ugazio7, Luciana Indinnimeo9Article first published online: 3 APR 2011

DOI: 10.1111/j.1399-3038.2011.01157.x

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Usefulness of Skin-Prick Tests in Children With Hand Eczema: Comparison With Their Use in Childhood and Adult Eczema.

Toledo F, Silvestre JF, Cuesta L, Latorre N, Monteagudo A.Source

Servicio de Dermatología, Hospital General de Alicante, Alicante, España.

AbstractBACKGROUND:

Hand eczema is not uncommon in children but it is rarely studied using skin-prick tests. Few reports have addressed their usefulness in children and none has specifically analyzed their use in children with hand eczema.

MATERIAL AND METHODS:

We performed a retrospective study of all children up to 16years of age with hand eczema who were assessed in the Department of Dermatology at Hospital General Universitario in Alicante, Spain with the standard GEIDAC panel over a 5-year period. We compared the epidemiologic data and results of skin-prick tests in this group with those obtained in children with eczema at any site and in adults with hand eczema.

RESULTS:

The study included a total of 1695 patients: 141 (8.3%) children and 1533 (91.7%) adults. Hand eczema was diagnosed in 496 (31.9%) adults and 32 (22.7%) children. Positive results were obtained in skin-prick tests in 50% of children with hand eczema compared with 37.6% of children with eczema at any site and 50.6% of adults with hand eczema. The current relevance of the positive allergens found in children with hand eczema (76.2%) was greater than that observed in children with eczema at any site (61%) or in adults with hand eczema (43%). The most common allergens in children with hand eczema were kathon CG and fragrance mix I, whereas in the other 2 groups metals were the most common. The most common final diagnosis in children with hand eczema was allergic contact dermatitis (34.3%), which proved to be more common than atopic dermatitis.

CONCLUSIONS:

We recommend the use of skin-prick tests in all children with chronic hand eczema.

European Survey Reveals Wide-Reaching Impact Of Eczema On Quality Of Life And Emotional Wellbeing Of Children And Their Families

RetweetMain Category: Eczema / Psoriasis
Also Included In: Dermatology; Pediatrics / Children's Health
Article Date: 11 Apr 2011 - 2:00 PDT

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Eczema impacts families, too

Staines, England — Childhood eczema can have a detrimental effect not only on children who suffer from the disorder, but also for their families, Medical New Today reports.

A survey carried out in eight European countries found that eczema can have a negative effect on all aspects of life, from participation in education to self-esteem, especially for children with the moderate-to-severe form.

Findings include:
• More than a quarter (27 percent) of children miss up to five days of school a year due to the disease.
• Nearly one-fifth (18 percent) miss out on sports and play.
• More than a quarter (26 percent) of parents have to miss time at work due to their child’s illness.

Investigators report that 50 percent of parents believe that the condition has a negative effect on their child’s self-esteem. Almost one-third of parents report that their children experience frustration (32 percent) and a feeling that they are different from other children (30 percent).

Parents also believe that their children feel “self-conscious” and “sad” some of the time because of their condition. Researchers also found that significant pain and discomfort, sleeping problems and mood swings are all problems experienced by one in four children with moderate-to-severe eczema.

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The development of socio-economic health differences in childhood: results of the Dutch longitudinal PIAMA birth cohort.

my BioMed Central TopAbstractBackgroundMethodsResultsDiscussionConclusionsCompeting interestsAuthors' contributionsAcknowledgementsReferencesPre-publication history

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Corticosteroid Use During Pregnancy Not Linked To Facial Clefts In Infants

RetweetAcademic Journal
Main Category: Pediatrics / Children's Health
Also Included In: Pregnancy / Obstetrics; Cleft Palate
Article Date: 11 Apr 2011 - 9:00 PDT

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European Survey Reveals Wide-Reaching Impact Of Eczema On Quality Of Life And Emotional Wellbeing Of Children And Their Families

RetweetMain Category: Eczema / Psoriasis
Also Included In: Dermatology; Pediatrics / Children's Health
Article Date: 11 Apr 2011 - 2:00 PDT

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Human atopic dermatitis complicated by eczema herpeticum is associated with abnormalities in IFN-γ response

font-family: Arial, Verdana, Helvetica, sans-serif;font-size: 13px;border-top: 1px solid #FF9A00;border-bottom: 1px solid #FF9A00;padding-top: 10px;padding-bottom: 10px

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Clinico-epidemiological and Mycological Aspects of Tinea Incognito in Iran: A 16-Year Study.

Ansar A, Farshchian M, Nazeri H, Ghiasian SA.Source

Dermatology Department, Hamadan University of Medical Sciences and Health Services, Hamadan, Iran.

AbstractBACKGROUND:

Tinea incognito is a dermatophytic infection in which topical or systemic steroids have modified the clinical appearance of the mycosis and mimicking other skin diseases.

OBJECTIVES:

A large retrospective study was carried out to identify the clinical aspects and type of dermatophytes involved in tinea incognito cases in Iran during 1993-2008. Patients: Out of 6325 subjects suspected to have dermatophytoses, 56 patients (29 males, 27 females, mean age 32.6 years) were affected with tinea incognito.

METHODS:

The causative agents were identified macroscopically and microscopically after the clinical samples were subjected to potassium hydroxide examination and culture isolation.

RESULTS:

The most common type of infection was tinea corporis (32.1%), which significantly affected male patients. The prevalence of the other tineas in decreasing order was as follows: tinea faciei (26.8%), tinea cruris (14.3%), tinea manuum (12.5%), tinea pedis (8.9%), and tinea capitis (5.4%). The clinical features were to some extent diverse, ranging from eczema-like, seborrhoeic dermatitis-like, pyoderma-like and folliculitis to alopecia on scalp, trunk and limbs. Trichophyton verrucosum was the most frequently isolated species representing 33.9% of isolates, followed by T.mentagrophytes (28.6%), T. rubrum (12.5%), Epidermophyton floccosum (10.7%), Microsporum canis (8.9%), T. violaceum (3.6%), and T. schoenleinii (1.8%).

CONCLUSION:

To the best of our knowledge, this is the first broad investigation dealing with tinea incognito in Iran. The etiological agents of tinea incognito in Iran are consistent with those of the general population.

PMID: 21441710

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Could good eczema care prevent development of other atopic conditions?

General PracticeHumansInfantPatient Education as TopicPractice Guidelines as TopicQuality of Health CareRhinitis, Allergic, Perennial/etiologyRhinitis, Allergic, Perennial/prevention & control

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An adolescent with marked hyperimmuno-globulinemia E showing minimal change nephrotic syndrome and a STAT3 gene mutation.

Miyazaki K, Miyazawa T, Sugimoto K, Fujita S, Yanagida H, Okada M, Takemura T.Source

Department of Pediatrics, Kinki University School of Medicine, Osaka, Japan.

Abstract

We encountered a patient with marked hyperimmunoglobulinemia E who had a mutation of the signal transducer and activator of transcription 3 gene (STAT3) and developed minimal change nephrotic syndrome (MCNS). From early infancy, the patient showed repeated episodes of refractory chronic eczema accompanied by impetigo vulgaris with cicatrization, as well as otitis media. Serum IgE was markedly increased (from 4,000 to 25,000 IU/ml). The nephrotic syndrome (NS) frequently relapsed, and was alternately responsive and resistant to corticosteroids. The STAT3 mutation was heterozygous, located in exon 23 of the transactivation domain and causing A744V substitution. Presently treated with mycophenolate mofetil, the patient has less frequent MCNS recurrences. Increases in circulating Th2 cytokines and IgE combined with suppression of the Th1 cytokine interferon-γ caused by the STAT3 abnormality, presumably caused MCNS by altering the Th1/Th2 balance among T-lymphocytes. To our knowledge, this is the first report of type I hyper-IgE syndrome (HIES) showing a STAT3 gene mutation and MCNS.

PMID: 21426892

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Deodorants are the leading cause of allergic contact dermatitis to fragrance ingredients*

, Torkil Menné1, Klaus E. Andersen2, Christian Avnstorp3, Berit Kristensen4, Ove Kristensen4, Knud Kaaber5, Grete Laurberg6, Niels Henrik Nielsen7, Mette Sommerlund8, Jens Thormann9, Niels K. Veien6, Susanne Vissing10, Jeanne D. Johansen1Article first published online: 12 APR 2011

DOI: 10.1111/j.1600-0536.2011.01889.x

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Quality of Life in a Population of Patients With Hand Eczema: A Six-month Follow-up Study.

Hald M, Agner T, Blands J, Johansen JD.Source

The National Allergy Research Centre, Gentofte University Hospital, Niels Andersens vej 65, DK-2900 Hellerup, Gentofte, Denmark. E-mail: marianne_hald

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Corticosteroid Creams Safe for Kids With Eczema: Study

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Related Researchers saw no worrisome side effects for those using the often effective medications.

THURSDAY, April 21 (HealthDay News) -- Long-term use of topical corticosteroids to treat children with the skin condition known as eczema doesn't cause any major negative side effects, according to a new study.

Many parents are concerned about the use of corticosteroid creams or lotions applied to the skin and this can lead to poorly managed eczema in children, the researchers explained. The most common fear among parents is that these ointments -- which contain steroids such as hydrocortisone or fluticasone -- will cause thinning of their child's skin. Some health care providers also share these concerns.

This study included 70 children who were treated with enough of the topical corticosteroids applied to the skin to consistently keep them virtually free of eczema, plus a control group of 22 children who didn't receive the medication.

During the study, all of the children were assessed for signs of corticosteroid-related side effects. There were no differences between the children receiving the medication and those in the control group.

"Our results show that normal routine use of topical corticosteroids does not cause skin thinning, and parents should be reassured. We hope that our work will give them the confidence to use topical corticosteroids safely and effectively," study leader Gayle Fischer, of the University of Sydney in Australia, said in a journal news release.

One expert was reassured by the findings.

"Cortisone phobia is prevalent around the world and results in the undertreatment of children and adults with eczema," noted Dr. Seth J. Orlow, chair of the department of dermatology at NYU Langone Medical Center, New York City, and Weinberg Professor of Pediatric Dermatology at the NYU School of Medicine.

"While the authors didn't examine for any internal effects of cortisone absorption, we usually assume local effects would typically predate systemic ones," he added. "Parents, pediatricians and others should take comfort that this study supports the excellent safety record of prescription topical cortisones when used appropriately under the guidance of a knowledgeable physician to control a child's eczema over extended periods of time."

The study is published in the current issue of the journal Pediatric Dermatology.

More information

The Nemours Foundation has more about eczema and children.

SOURCES: Seth J. Orlow, M.D., Ph.D., chair, department of dermatology, NYU Langone Medical Center and Weinberg Professor of Pediatric Dermatology at the NYU School of Medicine, New York City; Pediatric Dermatology, news release, April 21, 2011

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Correlation of Worldwide Incidence of Type 1 Diabetes (Diamond) With prevalence of Asthma and Atopic Eczema (ISAAC)

, Claudia Fsadni1, Stephen Fava1,2, Stephen Montefort1,2Article first published online: 10 MAY 2011

DOI: 10.1111/j.1752-699X.2011.00239.x

Issue

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Concerning heavy metals in childhood eczema

Kam Lun E. HonArticle first published online: 3 APR 2011

DOI: 10.1111/j.1399-3038.2010.01109.x

Issue

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Corticosteroid Creams Safe for Kids with Eczema

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Link Between Childhood Eczema, Hay Fever And Adult Allergic Asthma

RetweetMain Category: Respiratory / Asthma
Also Included In: Pediatrics / Children's Health; Allergy
Article Date: 16 Apr 2011 - 2:00 PDT

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Usefulness of Skin-Prick Tests in Children With Hand Eczema: Comparison With Their Use in Childhood and Adult Eczema.

Toledo F, Silvestre JF, Cuesta L, Latorre N, Monteagudo A.Source

Servicio de Dermatología, Hospital General de Alicante, Alicante, España.

AbstractBACKGROUND:

MATERIAL AND METHODS:

RESULTS:

CONCLUSIONS:

We recommend the use of skin-prick tests in all children with chronic hand eczema.

Use of topical corticosteroids in children with eczema does not have negative side effects

RetweetAcademic Journal
Main Category: Eczema / Psoriasis
Also Included In: Pediatrics / Children's Health; Dermatology
Article Date: 20 Apr 2011 - 21:00 PDT

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Kids' Eczema, Hay Fever Linked to Allergic Asthma Later

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MILIARY ECZEMA (Rhus Tox, Pulsatilla, Pulex Irritans, Staphysagria) Liquid [HomeoPet, LLC]

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E-learning program for medical students in dermatology

MoreClinicsversion ISSN 1807-5932Clinics vol.66 no.4 São Paulo 2011doi:10.1590/S1807-59322011000400016 CLINICAL SCIENCE

E-learning program for medical students in dermatology

Cristiana Silveira SilvaI; Murilo Barreto SouzaII; Roberto Silveira Silva FilhoIII; Luciana Molina de MedeirosI; Paulo Ricardo CriadoI

IDepartment of Dermatology, Universidade de São Paulo, São Paulo, SP, Brazil
IIDepartment of Medical Informatics, Faculdade de Medicina da FTC Salvador-Ba
IIISoftware Engineering from the Department of Informatics of the Donald Bren School of Information and Computer Sciences at University of California, Irvine, Ca

ABSTRACT

INTRODUCTION: Dermatological disorders are common in medical practice. In medical school, however, the time devoted to teaching dermatology is usually very limited. Therefore, online educational systems have increasingly been used in medical education settings to enhance exposure to dermatology.
OBJECTIVE: The present study was designed to develop a e-learning program for medical students in dermatology and evaluate the impact of this program on learning.
METHODS: This prospective study included second year medical students at the University of Technology and Science, Salvador, Brazil. All students attended discussion seminars and practical activities, and half of the students had adjunct online seminars (blended learning). Tests were given to all students before and after the courses, and test scores were evaluated.
RESULTS: Students who participated in online discussions associated with face-to-face activities (blended learning) had significantly higher posttest scores (9.0

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Use Of Topical Corticosteroids In Children With Eczema Does Not Have Negative Side Effects

RetweetAcademic Journal
Main Category: Eczema / Psoriasis
Also Included In: Pediatrics / Children's Health; Dermatology
Article Date: 20 Apr 2011 - 21:00 PDT

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Why is this little girl's eczema making her feel unwell?

20 Apr 11

Dr Keith Hopcroft explains how an apparent eczema flare-up turned out to be something much more serious.

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MILIARY ECZEMA (Rhus Tox, Pulsatilla, Pulex Irritans, Staphysagria) Liquid [HomeoPet, LLC]

How effective are skin products with DNA-repairing enzymes?

By Chris Woolston, Special to the Los Angeles Times June 6, 2011

The UV rays blasting down from the sun do more than burn your skin. They attack you right down to your DNA. That's why there's such a strong link between sun exposure and skin cancer.

If you could somehow repair the sun-damaged DNA in your skin, you could go a long way toward reducing your risk of skin cancer. As a bonus, your skin would look younger and healthier.

Related

View the Original article

Mimicry of hydroxyurea-induced leg ulcer by distal vena saphena parva insufficiency

Letter to the Editor

Tobias Goerge, Guenther Schellong, Rolf M. Mesters and Wolfgang E. Berdel

Download PDF (152.3 KB)View HTMLPermissions & Reprints Journal

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Kids’ Eczema, Hay Fever Linked to Allergic Asthma Later

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Can hypnotherapy ease eczema?

s now under control but flares up occasionally and he uses steroid cream. During his sleep he scratches his head and arms to the point where he breaks the skin. Would hypnotherapy stop him doing this?

A Hypnotherapy can sometimes be helpful in breaking addictive habits such as smoking but I think it would be of limited value in sorting out your boyfriend

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Denaturing gradient gel electrophoresis of neonatal intestinal microbiota in relation to the development of asthma.

my BioMed Central TopAbstractBackgroundMethodsResultsDiscussionConclusionsAbbreviationsCompeting interestsAuthors' contributionsAcknowledgementsReferences

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Descriptive Analysis of Cutaneous Recurrence Patterns in Patients with Melanoma.

Marcoval J, Ferreres JR, Penín RM, Piulats JM, Caminal JM, Fabra A.Source

Servicio de Dermatología, IDIBELL, Hospital Universitari de Bellvitge, Barcelona, España.

AbstractBACKGROUND AND OBJECTIVES:

Few studies have addressed cutaneous recurrence of melanoma. The aim of this retrospective study was to analyze the characteristics and prognostic significance of the different patterns of cutaneous recurrence.

MATERIAL AND METHODS:

Patients diagnosed with melanoma between 1988 and 2008 at Hospital de Bellvitge, Barcelona, Spain and for whom data were available for at least 2 years of follow-up were included in the study. Local recurrence was defined as melanoma invasion of the skin adjacent to the scar left by excision of the primary tumor, regional metastasis or recurrence as metastasis restricted to the area drained by a regional lymph node station, and distant cutaneous metastasis as metastasis occurring outside this area. The relationship between cutaneous recurrence pattern and age, sex, primary tumor site, tumor subtype, Breslow depth, and ulceration was assessed.

RESULTS:

Eighty-five out of 1,080 patients (7.87%) had cutaneous recurrence. In 71 of those patients (83.53%; 27 men and 44 women; mean age, 60.68 years), this was the first indication of melanoma recurrence. Thirty-two patients had local recurrence, 32 regional metastasis, and 7 distant metastasis. Significant differences were observed in survival time from diagnosis of the primary tumor (P

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Two Drugs Shown to Prolong Survival in Advanced Melanoma Cases

By Amanda Gardner
HealthDay ReporterLatest Cancer NewsCell Phone Use Might Raise Risk of Brain TumorsChemical Found in Foam Cups a Possible CarcinogenCancer CausesLate-Stage Cancer Patients' Chemo UnjustifiedBankruptcy Risk Doubles After Cancer DiagnosisWant More News? Sign Up for MedicineNet Newsletters!

SUNDAY, June 5 (HealthDay News) -- Two new drugs prolong the lives of patients with advanced melanoma, one of the deadliest forms of skin cancer and one that is notoriously difficult to treat, let alone cure.

The first treatment, vemurafenib, inhibits a gene mutation harbored in half of all melanoma patients, but is not yet approved by the U.S. Food and Drug Administration. The other drug, Yervoy (ipilumumab), is an immune system therapy that won approval in March.

Research on both drugs was presented Sunday at the annual meeting of the American Society of Clinical Oncology in Chicago while also being published simultaneously online in the New England Journal of Medicine.

"This is really a huge step toward personalized care in melanoma," Dr. Paul Chapman, lead author of the first study and the attending physician in the melanoma/sarcoma service at Memorial Sloan-Kettering Cancer Center in New York City, said in a statement. "This

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Novel Challenges for the Allergist

email citeulike Connotea Delicious citeulike Medicine Clinical Reviews in Allergy and ImmunologyDOI: 10.1007/s12016-011-8270-2Online First

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Children who suffer from Eczema may go on to develop Allergic Asthma once they reach adulthood

A new study reveals that children who suffer from eczema may go on to develop Adult Allergic Asthma once they reach their forties.

Children who suffer from childhood eczema, especially when it occurs with hay fever, are nine times more likely to develop allergic asthma once they reach their forties.

The study was carried out by University of Melbourne at the Murdoch Children’s Research Institute and has been following 1400 adults from when they were seven-years-old. The participants were assessed in 1968, at seven years of age where their allergies were studied along with their childhood environment. This study was then followed up in 2004, when all the participants were 44 years old.

Lead author Pamela Martin, a University of Melbourne PHD student, analysed the survey and skin prick data tests collected throughout the clinical study to see whether the occurrence of childhood eczema and hay fever lead to adult asthma.

She said:

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Lawn Mower Injuries Are on the Rise

Latest Prevention & Wellness NewsDistracted Driving May Be Rising Despite LawsRecord Temperatures Posing Health Risks in U.S.Lifestyle You Lead Today May Affect GenerationsToo Much Work, Food, Media May Be Hurting HealthWant More News? Sign Up for MedicineNet Newsletters!

Medical Organizations Urge Safety Precautions to Prevent Injuries to Children

By Bill Hendrick
WebMD Health News

Reviewed By Laura J. Martin, MD

June 3, 2011 -- Lawn-mowing safety precautions are essential to help reduce the thousands of injuries received every year by children and adolescents, five national medical organizations warn.

In 2010, about 253,000 people were treated for lawn-mower-related injuries; nearly 17,000 of those involved children under age 19, according to the U.S. Consumer Product Safety Commission.

And lawn mower injuries were up 3% in 2010 compared to 2009.

"Lawn mower injuries to children are easily preventable," says Keith Brandt, MD, president of the American Society for Reconstructive Microsurgery (ASRM), in a news release. "Children should remain inside the house or under direct supervision of another adult whenever a lawn mower is being used."

He says if another adult is not available to supervise, the person doing the cutting should "create a danger zone of 20 feet around the mower" and that the machine should be shut down if anyone gets within that distance.

Besides the American Society for Reconstructive Microsurgery, other organizations involved in issuing the warning include the American Society of Plastic Surgeons, American Society of Maxillofacial Surgeons, American Academy of Pediatrics, and American Academy of Orthopaedic Surgeons.

The organizations state in a news release that many injuries related to lawn mowers require a team of doctors from various specialties to treat and repair. Often, they say, patients must go through painful reconstructive operations for months or years to restore form and function.

Tips to Avoid Lawn Mower Injuries

The groups issued the following tips to reduce injuries:

Children should be at least 12 years old before they operate any lawn mower and at least 16 before they are allowed to operate a riding mower.Children should never be passengers on riding mowers.Operators of mowers should wear sturdy shoes, not sandals.Young children should be kept at a safe distance from the area being mowed.Adults should pick up stones, toys, and other debris from the lawn to prevent them from becoming flying objects that could cause injury.Mowers should be used that have a control that stops the machine from moving forward if the handle is released.Never pull backward or mow in reverse unless absolutely necessary, and carefully look for others when going backward is necessary.Eye and hearing protection should be used while mowing.

Lawn mowers can cause serious eye injuries. The American Academy of Pediatrics says children near lawn mowers that are in operation should wear polycarbonate protective eyewear.

Prevention of Injuries

"Every year at this time, it is common to see children operating or playing around lawn mowers in unsafe ways," says O. Marion Burton, MD, FAAP, president of the American Academy of Pediatrics. "We want parents and kids to be more aware of precautions to take so that injuries can be prevented."

Steven Buchman, MD, president of the American Society of Maxillofacial Surgeons, says a significant number of "devastating injuries" occur to children and adults that can be life-changing events.

Phillip Haeck, MD, president of the American Society of Plastic Surgeons, says he has seen "broken and dislocated bones, deep cuts, missing fingers and toes, limb amputations, burns, and eye injuries" caused by lawn mowers.

News Articles12345Next Article: Too Much Work, Food, Media May Be Hurting Health »

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Early diet and the risk of allergy: what can we learn from the prospective birth cohort studies GINIplus and LISAplus?

Sausenthaler S, Heinrich J, Koletzko S; for the GINIplus and LISAplus Study Groups.Source

Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany, and Ludwig-Maximilians-University of Munich, Dr von Hauner Children's Hospital, Munich, Germany.

Abstract

Recently, the American Academy of Pediatrics and the European Society of Pediatric Gastroenterology, Hepatology, and Nutrition published new guidelines on early nutrition and allergy prevention in infants and children. This article reviews epidemiologic evidence from 2 prospective German birth cohort studies, the GINIplus and the LISAplus, regarding maternal diet during pregnancy and feeding patterns in early life and the risk of allergy in light of the new recommendations. The 2 cohorts include a total of 9088 infants who were recruited within different regions of Germany between 1995 and 1999. A subgroup of 2252 infants with a hereditary risk of atopy was enrolled in a double-blind, randomized trial to investigate the effect of feeding regimen in infancy on the development of allergy with the strict recommendation that allergenic solid food be introduced late in the study. The results of the GINIplus and LISAplus studies mainly support the new finding regarding allergy prevention that a delayed introduction of solid foods or the avoidance of highly allergenic foods during the first year does not seem to be beneficial for allergy prevention. A very early introduction of solid foods and a high diversity before week 17 of age may increase the risk of later allergy. We showed that a high intake of margarine, vegetable oils, and some allergenic fruit and vegetables during pregnancy was associated with an increased risk of allergies, especially eczema. Because maternal diet during pregnancy is not reflected in the current recommendations, it should be the focus of future studies.

PMID: 21543544

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Pediatric allergy and immunology in Turkey

Gülfem Celik1, Arzu Bakirtas2, Cansin Sackesen3, İsmail Reisli4, Ayfer Tuncer3Article first published online: 2 MAY 2011

DOI: 10.1111/j.1399-3038.2011.01179.x

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Childhood eczema and hay fever leads to adult allergic asthma, study finds

ScienceDaily (Apr. 15, 2011) — Children who have eczema, particularly when occurring with hay fever, are nine times more likely to develop allergic asthma in their 40s, a new study reveals.

See Also:Health & MedicineAllergyAsthmaChildren's HealthPlants & AnimalsMiceVirologyBiologyLiving WellReferenceHay feverAllergenHouse dust miteEczema

The study was conducted by the University of Melbourne, the Murdoch Children's Research Institute, Menzies Research Institute and Monash University.

Published online in the Journal of Allergy and Clinical Immunology, the study reported on evidence from a clinical study of around 1400 grown up participants in the fifth decade follow-up of the Tasmanian Longitudinal Health Study (TAHS) which is the largest of its kind in the world.

In the TAHS, participants were assessed about their allergies and childhood environment in 1968, at seven years of age, and were followed up in 2004, at the age of 44.

Lead author Pamela Martin, a University of Melbourne PhD student based at the Murdoch Children Research Institute analysed the survey and skin prick testing data collected in the clinical study for the evidence of childhood eczema and hay fever leading to adult asthma. She said "In this study we see that childhood eczema, particularly when hay fever also occurs, is a very strong predictor of who will suffer from allergic asthma in adult life."

"The implications of this study are that prevention and rigorous treatment of childhood eczema and hay fever may prevent the persistence and development of asthma."

She also said this is the first study to distinguish between allergic and non-allergic asthma and their occurrence after childhood eczema and hay fever, as part of a sequence of allergic illnesses dubbed the 'atopic march'

Associate Professor Shyamali Dharmage, principal investigator of the TAHS and from the University of Melbourne's School of Population Health said currently few interventions are trialled to halt this march from childhood allergies to asthma.

"If successful strategies to stop the 'atopic march' are identified, this could ultimately save lives and health care costs related to asthma management and treatment."

The researchers estimate that up to 30 per cent of current allergic asthma within the larger population sample could be attributed to a history of childhood eczema and hay fever.

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Childhood eczema predicts adult asthma

MELBOURNE, April 15 (UPI) -- Children who have eczema are at increased risk of suffering from allergic asthma, researchers in Australia found.

Lead author Pamela Martin, a University of Melbourne doctoral student at the Murdoch Children Research Institute, analyzed survey data and skin prick testing data collected in the Tasmanian Longitudinal Health Study, which involved 1,400 participants. They were originally assessed about their allergies and childhood environment in 1968 at age 7 and were followed up in 2004, at age 44.

The study, published online in the Journal of Allergy and Clinical Immunology, estimated that as much as 30 percent of current allergic asthma could be attributed to a history of childhood eczema and hay fever.

"In this study we see that childhood eczema, particularly when hay fever also occurs, is a very strong predictor of who will suffer from allergic asthma in adult life," Martin says in a statement. "The implications of this study are that prevention and rigorous treatment of childhood eczema and hay fever may prevent the persistence and development of asthma."

© 2011 United Press International, Inc. All Rights Reserved. Any reproduction, republication, redistribution and/or modification of any UPI content is expressly prohibited without UPI's prior written consent.

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BOILS ECZEMA (Sarsaparilla Root) Pellet [Natural Health Supply]

Brown Fat Cells May One Day Help Combat Obesity

Latest Diet & Weight Management NewsWhy Smokers Gain Weight When QuittingWeight-Loss Surgery May Not Lower Death RiskSleep-Deprived People May Crave High-Calorie FoodsDieters More Likely to Trust Food PackagingHeart-Healthy DASH Diet May Help Teen GirlsWant More News? Sign Up for MedicineNet Newsletters!

SUNDAY, June 5 (HealthDay News) -- The human body has two kinds of fat: the "bad" white kind that stores calories and the "good" brown kind that burns them. Now, researchers say that it is actually possible to make more brown fat to help people lose weight.

"We are now even more optimistic that brown fat could be used for treating obesity and diabetes," study lead author Dr. Aaron Cypess, assistant professor at Harvard Medical School and the Joslin Diabetes Center in Boston, said in a news release from the Endocrine Society.

In 2009, Cypess showed that although adults tend to have a lot more white fat than they do brown, most have some brown fat in an area extending from the front of their neck to their chest.

Now, in a follow-up study, scheduled for presentation Sunday at the Endocrine's Society's annual meeting in Boston, Cypess found more good brown fat cells also exist in deeper fat. In fact, some of them were actually mixed in with white fat cells.

"It's a marbling at the cellular level," Cypess said in the news release. "We wondered: Wouldn't it be nice if you could grow more brown fat? The answer is yes."

The researchers grew mature human brown fat cells from pre-adipocytes, or pre-fat cells, taken from a fresh sample of brown fat. Cypess noted that the process, which took about two weeks in a lab, would probably happen more quickly in the body.

By measuring the oxygen consumption rate of fat cells, the researchers also demonstrated that brown fat does in fact burn a significant number of calories. Although the study concluded that stimulating the growth of additional brown fat may be a promising treatment for obesity, the researchers stressed that making more good fat would not be a substitute for proper diet and exercise.

"As powerful as brown fat could be at burning calories, we can easily out-eat the benefit," Cypess warned.

Because this study was presented at a medical meeting, the findings should be viewed as preliminary until they are published in a peer-reviewed journal.

-- Mary Elizabeth Dallas

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Methotrexate and Azathioprine Effective for Severe Eczema

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Skin Sensitivity To Food Allergens Explained

Atopic dermatitis is a form of eczema that is caused by an inappropriate inflammatory response in the skin. Many children with atopic dermatitis also have food allergies, and skin contact with food allergens can make their atopic dermatitis worse. It is unclear why this occurs, but it has been suggested that immune cells known as T cells that are sensitized by exposure to food allergens in the gut are responsible. Raif Geha and colleagues, at Harvard Medical School, Boston, have now generated data in a mouse model of food allergen

View the Original article

Childhood eczema and hay fever leads to adult allergic asthma

Children who have eczema, particularly when occurring with hay fever, are nine times more likely to develop allergic asthma in their 40s, a new study reveals.

The study was conducted by the University of Melbourne, the Murdoch Childrens Research Institute, Menzies Research Institute and Monash University.

In the TAHS, participants were assessed about their allergies and childhood environment in 1968, at seven years of age, and were followed up in 2004, at the age of 44.

She said "In this study we see that childhood eczema, particularly when hay fever also occurs, is a very strong predictor of who will suffer from allergic asthma in adult life."

"The implications of this study are that prevention and rigorous treatment of childhood eczema and hay fever may prevent the persistence and development of asthma."

Associate Professor Shyamali Dharmage, principal investigator of the TAHS and the University of Melbourne's School of Population Health said currently few interventions are trialled to halt this march from childhood allergies to asthma.

"If successful strategies to stop the 'atopic march' are identified, this could ultimately save lives and health care costs related to asthma management and treatment."

The researchers estimate that up to 30 per cent of current allergic asthma within the larger population sample could be attributed to a history of childhood eczema and hay fever.

###

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MILIARY ECZEMA (Rhus Tox, Antimonium Crudum, Pulux Irritans, Staphysagria) Liquid [HomeoPet, LLC]

Pediatric allergy and immunology in Italy

DOI: 10.1111/j.1399-3038.2011.01157.x

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Wheal Size Predicts Food Allergy Resolution in Children

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Wednesday, June 15, 2011

The atopy patch test: is it time to redefine its significance?

tin.it

AbstractOBJECTIVE:

The atopy patch test (APT) was recently defined as an important tool in the diagnosis of atopic eczema/dermatitis syndrome (AEDS). Recent data showed that the APT may be positive also in patients with rhinitis or asthma. We examined the mechanisms that could underlie such findings.

DATA SOURCE:

To locate relevant articles pertaining to the use of APT, MEDLINE databases from 1989 (when the APT was first introduced) to the present were searched.

STUDY SELECTION:

Articles concerning the results of APT in patients with AEDS and with rhinitis or asthma attributable to sensitization to inhalant allergens were examined.

RESULTS:

Recent data show that APT to dust mites is frequently positive, and it may be the only positive test, not only in subjects with AEDS but also in subjects with only respiratory symptoms (rhinitis, asthma) and a history of AEDS. Instead, positive skin prick tests and in vitro immunoglobulin (Ig) E tests prevail in patients with a negative history for AEDS.

CONCLUSION:

Based on the pathophysiology of AEDS, in which the mechanisms of delayed hypersensitivity are predominant, the APT seems to have a greater significance than skin prick tests or in vitro IgE tests in patients with current or past history of AEDS. That different sensitization mechanisms underlie these different clinical expressions seems conceivable. In particular, if mite allergens enter the skin in the presence of a filaggrin-dependent skin barrier dysfunction, the sensitization mechanism seems to be ultimately revealed by a positive APT.

Pseudoceramide for childhood eczema: does it work?

Hon KL, Wang SS, Lau Z, Lee HC, Lee KK, Leung TF, Luk NM.Source

Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong. ehon

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Alcohol and skin disorders: with a focus on psoriasis.

Kazakevich N, Moody MN, Landau JM, Goldberg LH.Source

Well Cornell Medical College, Methodist Hospital, Houston, TX, USA; DermSurgery Associates, Houston, TX, USA; Department of Dermatology, The University of Texas Medical School at Houston, Houston, TX USA.

Abstract

Alcohol is a serious cause of morbidity and mortality in our society and is implicated in multiple health conditions, including hepatic failure, neurological damage, hematological disorders, and nutritional deficiencies, to name a few. Although alcohol induced cutaneous abnormalities can also cause significant morbidity, they tend to be overshadowed by the other disease states associated with alcohol use. In addition to the cutaneous stigmata linked to chronic alcoholic liver disease, alcohol can directly cause or exacerbate several skin conditions. In particular, alcohol misuse is implicated in the development of psoriasis and discoid eczema, as well as confers increased susceptibility to skin and systemic infections. Alcohol misuse might also exacerbate rosacea, porphyria cutanea tarda, and post adolescent acne. Herein, we review the evidence concerning the influences of alcohol in skin conditions with a focus on psoriasis.

PMID: 21611681

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Painful, itchy skin linked to obesity in kids

Tweet Share this EmailPrint Related NewsDoctors lack data on LGBT community: reportThu, Mar 31 2011Half a million die from smoking yearly in U.S.Thu, Mar 31 2011Special report: When the drugs don't workThu, Mar 31 2011Reliable? Heart studies often exclude the elderlyMon, Mar 28 2011FDA approves Bristol-Myers melanoma drugFri, Mar 25 2011 Analysis & Opinion4 ways to add inflation protection to your retirement planSchool on Wheels Related Topics Health » By Leigh Krietsch Boerner

NEW YORK

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